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SLU-PP-332 is a small-molecule ERR (Estrogen-Related Receptor) pan-agonist that activates ERRΞ±, ERRΞ² and ERRΞ³ simultaneously. It mimics the transcriptional effects of endurance exercise at the cellular level.
Key Research Areas
- Activates all three ERR isoforms β mimics exercise-induced gene expression
- Studied for mitochondrial biogenesis and increased oxidative capacity
- Promotes fatty acid oxidation and metabolic flexibility in muscle tissue
- Studied for endurance enhancement in preclinical exercise models
- Potential applications in metabolic disease, obesity and muscle wasting research
Mechanism of Action
SLU-PP-332 binds the ligand-binding domain of ERRΞ±/Ξ²/Ξ³, activating transcription of PGC-1Ξ± target genes involved in mitochondrial biogenesis, fatty acid oxidation and oxidative phosphorylation.
π¬ β₯99% by HPLC | Sterile lyophilised powder | Supplied in clear borosilicate glass vial
