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NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme found in every living cell. It plays a central role in energy metabolism, DNA repair, and the regulation of longevity-associated pathways.
Key Research Areas
- Essential cofactor for over 500 enzymatic reactions in cellular metabolism
- Activates sirtuins (SIRT1โSIRT7) โ key regulators of ageing and longevity
- Supports PARP-mediated DNA repair mechanisms
- Studied for mitochondrial function and energy production
- Declines with age โ supplementation studied for age-related metabolic decline
Mechanism of Action
NAD+ is a hydride-accepting coenzyme in glycolysis, the TCA cycle and oxidative phosphorylation. It also serves as a substrate for sirtuins and PARPs, linking energy metabolism to epigenetic regulation and DNA repair.
๐ฌ โฅ99% by HPLC | Sterile lyophilised powder | Supplied in clear borosilicate glass vial
